Some barbed drain uncloggers are designed to be single-use, disposable tools. However, it is possible to clean and reuse them.
Straight after use, pull off all the debris which has been collected. Then you can simply rinse your unclogger and wipe if necessary.
The barbed drain unclogger can then be kept, until the barbs are past their best, in your garage, shed, under the kitchen sink or can even be hung up by its looped handle.